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SAMe is a supplement formed in the body by an enzymatic reaction between adenosine-triphosphate ATP and methionine.nbsp It was discovered in 1952 in Italy and has been researched and manufactured there.nbsp SAMe works closely with folic acid and vitamin B-12 and functions as a methyl donor.nbsp This nutrient carries and donates methyl molecules necessary to facilitate the manufacture of DNA and brain neurotransmitters. Tissue levels of SAMe are typically low in the elderly. Serving Size:1 Tablet Suggested Use:As a dietary supplement, take 1 tablet, 2 to 4 times daily, preferably on an empty stomach. Refrigeration recommended after opening.Free of:sugar, starch, yeast, wheat, gluten, corn, soy, milk or preservatives. Other Ingredients:Cellulose, Croscarmellose Sodium, Methacrylic Acid, Magnesium Stearate Vegetable Source, Silica, Triethyl Citrate, Stearic Acid Vegetable Source, Citric Acid and Ascorbic Acid. Warnings:Individuals with bipolar manic depression should not take SAMe unless

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